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Alexey V Fedulov


Alexey V Fedulov

Alpert School of Medicine of Brown University–Rhode Island Hospital, USA

Biography

Alexey V Fedulov has his expertise in Epigenetic Engineering and Transgenerational Epigenetic Studies. His lab has built a model of targeted reactivation of epigenetically silenced genes by fusion complexes comprised of DNA demethylase enzymes and sequence-specific DNA binding domains. His laboratory studies are in immune and epigenetic mechanisms of lung disease including early life asthma origins. The ultimate goal of the studies is to find novel therapeutic approaches by modulating epigenetic
control of gene expression.

Abstract

Abstract : Maternal exposure to environmental particles leads to transgenerational epigenetic transmission of asthma risk